Thomas S Kilduff Selected Research

TAK-925

1/2023

Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK-925 and ARN-776 in narcoleptic orexin/tTA; TetO-DTA mice.

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Thomas S Kilduff Research Topics

Disease

17	Narcolepsy 10/2023 - 07/2011
13	Cataplexy 10/2023 - 03/2013
7	Sleep Wake Disorders 10/2023 - 05/2014
5	Disorders of Excessive Somnolence (Hypersomnia) 01/2021 - 04/2015
5	Sleep Deprivation 01/2019 - 12/2002
4	Sleep Initiation and Maintenance Disorders (Insomnia) 09/2023 - 03/2010
3	Pain (Aches) 01/2017 - 01/2011
2	Nerve Degeneration 12/2022 - 11/2021
1	Sleepiness 01/2021
1	Cognitive Dysfunction 10/2020
1	Mental Disorders (Mental Disorder) 01/2018
1	Autism Spectrum Disorder 10/2017
1	Migraine Disorders (Migraine) 01/2017
1	Huntington Disease (Huntington's Disease) 02/2016
1	Lethargy 04/2015
1	Fragile X Syndrome (Martin Bell Syndrome) 04/2015
1	Body Weight (Weight, Body) 05/2014
1	Central Nervous System Diseases (CNS Diseases) 12/2012
1	Substance-Related Disorders (Drug Abuse) 07/2006

Drug/Important Bio-Agent (IBA)

20	OrexinsIBA 10/2023 - 07/2006
3	Antidepressive Agents (Antidepressants)IBA 01/2019 - 04/2015
2	Peptides (Polypeptides)IBA 10/2023 - 05/2014
2	trans-sodium crocetinate (crocetin)IBA 01/2023 - 01/2023
2	Doxycycline (Periostat)FDA LinkGeneric 12/2022 - 05/2014
2	NeuropeptidesIBA 11/2021 - 01/2017
2	Neurotransmitter Agents (Neurotransmitter)IBA 11/2021 - 01/2021
2	almorexantIBA 10/2020 - 03/2013
2	Sodium Oxybate (gamma Hydroxybutyrate)FDA Link 01/2019 - 01/2017
2	Ataxin-3IBA 05/2014 - 03/2013
2	Diphtheria ToxinIBA 05/2014 - 05/2014
1	Opioid Analgesics (Opioids)IBA 09/2023
1	Vasoconstrictor AgentsIBA 01/2023
1	TAK-925IBA 01/2023
1	Orexin ReceptorsIBA 01/2021
1	AminesIBA 01/2021
1	Biogenic Amines (Biogenic Amine)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Zolpidem (Ambien)FDA LinkGeneric 10/2020
1	Methylphenidate (Ritalin)FDA LinkGeneric 01/2019
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2019
1	Amphetamine (Amfetamine)FDA LinkGeneric 01/2019
1	CatecholaminesIBA 01/2019
1	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 01/2019
1	solriamfetolIBA 01/2019
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2019
1	Modafinil (Provigil)FDA Link 01/2019
1	pitolisantIBA 01/2019
1	Serotonin (5 Hydroxytryptamine)IBA 01/2019
1	Antipsychotic Agents (Antipsychotics)IBA 01/2018
1	Trace amine-associated receptor 1IBA 11/2017
1	4- (3- fluoro- 2- methylphenyl)- 4,5- dihydrooxazol- 2- ylamineIBA 11/2017
1	Controlled SubstancesIBA 11/2017
1	RO5256390IBA 11/2017
1	neuroligin 3IBA 10/2017
1	Eszopiclone (Lunesta)FDA Link 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 01/2017
1	Indicators and Reagents (Reagents)IBA 02/2016
1	2- chloro- 4- (1- (4- fluorophenyl)- 2,5- dimethyl- 1H- imidazol- 4- ylethynyl)pyridineIBA 04/2015
1	pyridineIBA 04/2015
1	Baclofen FDA LinkGeneric 05/2014
1	Hypnotics and Sedatives (Sedatives)IBA 03/2013
1	4- (3,4- dichlorophenyl)- 4,5- dihydrooxazol- 2- ylamineIBA 12/2012
1	4-nitrophenethyl bromide (NPB)IBA 01/2011
1	nelotanserinIBA 03/2010
1	Urea (Carbamide)FDA LinkGeneric 03/2010
1	GABA-B Receptor AgonistsIBA 07/2006
1	GABA-B ReceptorsIBA 07/2006
1	CalciumIBA 07/2006
1	Messenger RNA (mRNA)IBA 12/2002
1	AlbuminsIBA 12/2002
1	Carrier Proteins (Binding Protein)IBA 12/2002

Therapy/Procedure

5	Therapeutics 11/2021 - 05/2014
1	Aftercare (After-Treatment) 01/2023
1	Drug Therapy (Chemotherapy) 01/2019